Assay Development & Technical Leadership
The Staff Scientist will provide scientific and technical leadership for biomarker assay development, with a focus on antibody-based methods for measuring protein biomarkers in blood, cerebrospinal fluid, and other biological matrices. Key responsibilities include:
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Selecting, characterizing, and evaluating antibodies and other affinity reagents
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Designing and executing assay-development strategies
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Optimizing experimental conditions and troubleshooting complex technical issues
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Establishing approaches to assess assay sensitivity, specificity, precision, reproducibility, and robustness
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Developing standardized laboratory protocols and quality-control procedures
Biomarker Analysis & Translational Research
The Staff Scientist will lead the analytical evaluation of candidate biomarkers relevant to Parkinson’s disease pathology, diagnosis, disease progression, and therapeutic response. This includes:
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Designing experiments and interpreting biomarker data
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Evaluating assay performance against defined criteria
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Integrating laboratory findings with broader translational and clinical research objectives
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Advancing promising assays from early-stage development toward use in observational studies, clinical trials, and therapeutic development
Team Leadership & Collaboration
The Staff Scientist will provide day-to-day scientific guidance to laboratory personnel, oversee experimental activities and assay-development projects, and mentor junior scientists and research staff. The individual will collaborate closely with investigators, clinicians, and external partners to:
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Establish project priorities and interpret findings
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Align biomarker development efforts with clinical and research goals
Scientific Contribution & Program Development
The Staff Scientist will contribute to the overall scientific direction of the biomarker program, including:
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Identifying emerging biomarker technologies and developing new research approaches
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Preparing scientific reports and manuscripts for publication
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Presenting findings at internal and external scientific meetings