Research Scientist II/Senior, Discovery Machine Learning
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Before you apply
SalaryNo pay range posted
LocationSan Diego HQ
Work modeon-site
Typefull-time
SenioritySenior
Experience3+ yrs
DepartmentScience
Company size201–500 people
PostedJun 15, 2026 · 4mo ago
Verified live1d ago
May no longer be actively hiring
Posted by the company on Jun 15, 2026No pay range listed, though California requires one
At a glanceSummarised by Seekless from the posting.
PhD or equivalent degree in chemistry or another physical science with 3+ years of experience
Familiarity with using statistical analysis techniques to evaluate, troubleshoot, and adapt models in scientific contexts
Excellent written and verbal communication skills; must be able to articulate complex scientific concepts, technical challenges, and results clearly and concisely to diverse audiences
Python programming
Statistics
Drug discovery
PhD or equivalent degree in computational chemistry or machine learning in chemistry
3+ years of experience working in a drug discovery project
Skills
Python
statistics
drug discovery
Benefits
Health insurance
Flexible spending accounts
Voluntary life insurance
401(k) matching
Flexible time off
About the role
JOB SUMMARY
We are seeking skilled scientists to join our Discovery Machine Learning group at Iambic Therapeutics. In this role, you will be a key player in applying advanced ML techniques to support our drug discovery efforts and will be part of drug discovery teams pursuing important therapeutics across multiple indications. The work will include focus on our flagship machine learning models, including Enchant, our multimodal transformer model for predicting drug-target interactions and molecular properties. This role is based at our San Diego headquarters.
Responsibilities
KEY RESPONSIBILITIES
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Train, fine-tune, and evaluate machine learning models, assessing how they can best be leveraged in a drug-discovery setting and optimizing their performance
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Partner with computational chemists, medicinal chemists and biologists to leverage ML insights for decision-making in high-throughput design-make-test-analyze cycles
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Generate value, internally and for partners, from our machine learning models, and collaborate with other discovery teams to shape their use
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Communicate results with internal drug discovery teams and machine learning scientists and externally with partners
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Support the evolution of our machine learning models by gathering analytical feedback and delivering domain-driven guidance to the machine learning team
Requirements
QUALIFICATIONS
Required:
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PhD or equivalent degree in chemistry or another physical science with 3+ years of experience or commensurate degree and job experience. More junior candidates are welcome to apply, title will reflect experience.
•
Familiarity with using statistical analysis techniques to evaluate, troubleshoot, and adapt models in scientific contexts
•
Excellent written and verbal communication skills; must be able to articulate complex scientific concepts, technical challenges, and results clearly and concisely to diverse audiences.
•
Skills: Python programming, statistics, drug discovery
Nice to have
Strongly preferred:
•
PhD or equivalent degree in computational chemistry or machine learning in chemistry
•
3+ years of experience working in a drug discovery project
About the company
ABOUT IAMBIC THERAPEUTICS
Iambic Therapeutics (Nasdaq: IAM) is a technology and clinical-stage life sciences company headquartered in San Diego. By utilizing molecular superintelligence — integrating proprietary AI with automated, scalable chemistry and biology experimentation — our platform is designed to address the totality of drug discovery and development. At Iambic, we are building an engine that is designed to power the future of medicine. Learn more at iambic.ai.
MISSION & VALUES
Our mission is to make better technology for better medicines. Three values guide how we work:
•
Bold. We are courageous, take thoughtful risks, and approach challenges with tenacity.
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Innovative. We are creative and find new solutions that deliver impact.
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Collaborative. We respect one another and partner with integrity.
We value the range of perspectives our people bring, and we work to build an environment where every team member can contribute and grow.
Benefits
PAY AND BENEFITS
The pay range for this role is listed above. Actual pay depends on factors including experience, skills, and location. Eligible employees in the U.S. receive company-paid medical coverage, flexible spending accounts, voluntary life insurance, 401(k) matching and flexible time off. We are in a brand-new state-of-the art facility in beautiful San Diego with a community gym, dining, and easy access to great places to live and play.
Legal
EQUAL OPPORTUNITY
Iambic is an equal opportunity employer. We consider all qualified applicants without regard to race, color, religion, sex, sexual orientation, gender identity or expression, national origin, ancestry, age, disability, medical condition, genetic information, marital status, veteran or military status, or any other characteristic protected by law.