Principal Scientist, Lab Head, Immunology, Cell Therapy
Salary$143k – $266k
LocationSouth San Francisco
Work modeon-site
Typefull-time
SeniorityLead
Experience5+ yrs
Company size10,000+ people
PostedJul 29, 2026 · 2mo ago
Verified live5h ago
At a glanceSummarised by Seekless from the posting.
Must have15
Lead a highly productive research group focused on designing next-generation cell therapies to treat autoimmune diseases
Integrate efforts across cross-functional teams to identify new targets and therapeutic hypotheses
Advance transformative therapeutics from preclinical studies into early clinical development
Deep understanding of cellular immunology principles and pathways relevant to autoimmune disease (inflammatory bowel disease, multiple sclerosis, lupus, chronic obstructive pulmonary disease)
Excellent communication skills
Lead and manage a highly-productive research team
Generate high-quality, original research that advances understanding of autoimmune disease
Contribute directly to initiation and advancement of novel pipeline projects
PhD and postdoctoral training in Immunology, Cell Biology or related field
Minimum of 5 years post-PhD experience with a record of high-impact publications (preprints considered), patents, and/or a proven track record advancing therapeutic candidates from pipeline entry to early clinical development
Demonstrated expertise in cellular immunology and deep understanding of pathways and immune cell types that contribute to autoimmune disease
Outstanding leadership and a collaborative spirit, with a proven track record of working with multidisciplinary teams
Excellent written and verbal communication skills
Exceptional critical thinking skills, commitment to rigorous experimental design and creative problem-solving
Demonstrated ability to use data-driven insights to guide scientific decisions
Nice to have3
Expertise in both B cell and T cell biology
Experience engineering, modifying, and functionally evaluating human immune cells
Experience working with mouse models, including humanized models
Skills
human immune cells
Benefits
Relocation benefits
Discretionary annual bonus
THE OPPORTUNITY
The Department of Immunology Discovery at Genentech is excited to announce an opportunity for a Principal Scientist, Lab Head, to lead a research group focused on designing next-generation cell therapies to treat autoimmune diseases.
The successful candidate will lead a highly productive research team, integrating efforts across cross-functional teams to identify new targets and therapeutic hypotheses, and to advance transformative therapeutics from preclinical studies into early clinical development. The ideal candidate will have a deep understanding of cellular immunology principles and pathways relevant to the biology of autoimmune disease, including but not limited to inflammatory bowel disease, multiple sclerosis, lupus and chronic obstructive pulmonary disease. Excellent communication skills are essential to facilitate fruitful collaborations with colleagues across a diverse array of departments, including computational biology, proteomics and tissue genomics, drug development, early clinical development, and translational medicine.
Responsibilities
Key responsibilities include leading and managing a highly-productive research team, generating high-quality, original research that advances our understanding of autoimmune disease and contributing directly to the initiation and advancement of novel pipeline projects. The successful candidate may also play a critical role within cross-functional teams evaluating external business development opportunities to accelerate our cell therapy pipeline.
WHO YOU ARE
The ideal candidate will have:
•
PhD and postdoctoral training in Immunology, Cell Biology or related field
•
A minimum of 5 years post-PhD experience with a record of high-impact publications (preprints considered), patents, and/or a proven track record advancing therapeutic candidates from pipeline entry to early clinical development
•
Demonstrated expertise in cellular immunology and a deep understanding of pathways and immune cell types that contribute to autoimmune disease
•
Outstanding leadership and a collaborative spirit, with a proven track record of working with multidisciplinary teams
•
Excellent written and verbal communication skills, with the ability to communicate complex scientific concepts to multidisciplinary audiences
•
Exceptional critical thinking skills, a commitment to rigorous experimental design and creative problem-solving, and a demonstrated ability to use data-driven insights to guide scientific decisions
Preferred qualifications:
•
Expertise in both B cell and T cell biology
•
Experience engineering, modifying, and functionally evaluating human immune cells
•
Experience working with mouse models, including humanized models
Benefits
Relocation benefits are available for this job posting.
The expected salary range for this position based on the primary location of California is $143,200 to $265,900. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. A discretionary annual bonus may be available based on individual and Company performance. This position also qualifies for the benefits detailed at the link provided below.
Benefits
Legal
Genentech is an equal opportunity employer. It is our policy and practice to employ, promote, and otherwise treat any and all employees and applicants on the basis of merit, qualifications, and competence. The company’s policy prohibits unlawful discrimination, including but not limited to, discrimination on the basis of Protected Veteran status, individuals with disabilities status, and consistent with all federal, state, or local laws.
If you have a disability and need an accommodation in relation to the online application process, please contact us by completing this form Accommodations for Applicants.