TE
TempusNGS Senior Scientist 1
Salary$95k – $120k
LocationChicago
Typefull-time
SenioritySenior
DepartmentR&D
EquityIncluded
Company size1,001–5,000 people
PostedOct 6, 2026 · 1w ago
Verified live1d ago
At a glanceSummarised by Seekless from the posting.
Ph.D. with 0 or more years of experience, or Master's degree with 5+ years of relevant experience in molecular biology, assay development, or a related field
Experience in assay development and/or validation required
Experience in a clinical laboratory environment required
Strong analytical, troubleshooting, and experimental design skills
Highly organized, detail-oriented, and committed to quality and accuracy
Proven ability to learn quickly and adapt to new processes, technologies, and workflows
Strong collaboration skills with the ability to lead across teams
Excellent oral and written communication skills
Ability to manage competing priorities and deadlines in a dynamic environment
Travel up to 10% as needed
CAP/CLIA/NYSDOH experience preferred
DNA/RNA extraction and purification methods
NGS library preparation, hybrid capture, and sequencing workflows
PCR-based techniques, including PCR, qPCR, RT-PCR, and ddPCR
Nucleic acid manipulation, quantitation, and analysis
Assay troubleshooting, root cause analysis, and workflow optimization
Experience with liquid biopsy workflows
Experience with laboratory automation and liquid handling robotics
Experience developing and implementing protocols for CLIA-regulated laboratories
Familiarity with LIMS and laboratory data systems
We are an equal opportunity employer
Skills
DNA extraction
RNA extraction
NGS library preparation
hybrid capture
sequencing
PCR
qPCR
RT-PCR
ddPCR
liquid biopsy workflows
laboratory automation
liquid handling robotics
LIMS
Benefits
Health insurance
Incentive compensation
Restricted stock units
Medical benefits
Passionate about precision medicine and advancing the healthcare industry?
Recent advancements in underlying technology have finally made it possible for AI to impact clinical care in a meaningful way. Tempus’ proprietary platform connects an entire ecosystem of real-world evidence to deliver real-time, actionable insights to physicians, providing critical information about the right treatments for the right patients, at the right time.
About the role
We are seeking a Senior Scientist to lead the development and validation of new molecular assays and laboratory processes for deployment in our clinical laboratory.
What You’ll Do
•
Lead development of molecular assays and NGS workflows for high-throughput clinical laboratories.
•
Design, execute, and analyze R&D studies with scientific rigor and attention to detail.
•
Lead assay validation and clinical implementation from study design through launch, including workflow development, SOP creation, and documentation.
•
Design and execute qualification and validation studies for reagents, instruments, equipment, and methods to support clinical deployment.
•
Interpret data, troubleshoot issues, and drive process improvements.
•
Collaborate across cross-functional teams and provide scientific leadership in a matrixed environment.
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Communicate clearly and effectively with technical and non-technical stakeholders.
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Train and mentor junior scientific staff and support implementation of new laboratory workflows.
•
Support automation and technology initiatives to improve laboratory workflows.
•
Manage multiple priorities and adapt quickly in a fast-paced environment.
•
Travel up to 10% as needed.
Qualifications
•
Ph.D. with 0 or more years of experience, or Master’s degree with 5+ years of relevant experience in molecular biology, assay development, or a related field.
•
Experience in assay development and/or validation required.
•
Experience in a clinical laboratory environment required; CAP/CLIA/NYSDOH experience preferred.
•
Strong analytical, troubleshooting, and experimental design skills.
•
Highly organized, detail-oriented, and committed to quality and accuracy.
•
Proven ability to learn quickly and adapt to new processes, technologies, and workflows.
•
Strong collaboration skills with the ability to lead across teams.
•
Excellent oral and written communication skills.
•
Ability to manage competing priorities and deadlines in a dynamic environment.
Preferred Technical Experience
•
DNA/RNA extraction and purification methods.
•
NGS library preparation, hybrid capture, and sequencing workflows.
•
PCR-based techniques, including PCR, qPCR, RT-PCR, and ddPCR.
•
Nucleic acid manipulation, quantitation, and analysis.
•
Assay troubleshooting, root cause analysis, and workflow optimization.
Highly Desirable
•
Experience with liquid biopsy workflows.
•
Experience with laboratory automation and liquid handling robotics.
•
Experience developing and implementing protocols for CLIA-regulated laboratories.
•
Familiarity with LIMS and laboratory data systems.
Pay Range: $95,000 - $120,000 USD
Benefits
The expected salary range may vary for other locations. Actual salary may vary based on qualifications and experience. Tempus offers a full range of benefits, which may include incentive compensation, restricted stock units, medical and other benefits depending on the position.
Legal
We are an equal opportunity employer. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status.