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Vertex

Clinical Development Senior Medical Director-Neurology

Salary$281k – $421k
LocationBoston, MA
Work modehybrid
Typefull-time
SeniorityDirector
Experience12+ yrs
EquityIncluded
Company size10,000+ people
First seenOct 7, 2026 · 4d ago
Verified live1d ago
At a glanceSummarised by Seekless from the posting.
Must have7
MD, DO or equivalent ex-US medical degree
Typically requires 12 years Pharmaceutical/Biotech industry experience, including time managing clinical trials and clinical development programs
Ability to work collaboratively in a fast-paced, team-based matrix environment
Ability to work independently to resolve challenges
Enterprise-wide thinking and ability to work in ambiguity
Ability to ensure the completeness of team work
Excellent oral and written communication skills
Nice to have2
Global clinical research experience, and experience interacting with regulatory authorities is highly desired
Board certification/eligibility in a specialty is highly desired
Benefits
Health insurance
Dental insurance
Vision insurance
Paid time off
Educational assistance
Student loan repayment
Commuting subsidy
Matching charitable donations
401(k)
Job Description
General Summary:
The Senior Medical Director will define the clinical development strategy of an asset, work with cross-functional multidisciplinary teams to define overall asset strategy as well as clinical trials strategy, design and execution, and may serve as the Medical Lead for clinical trials that will be conducted with these compounds.
Key Duties and Responsibilities:
•
Defines a clinical development strategy and prepare the clinical development plans, in conjunction with other relevant functional areas
•
Participates in the development of study protocols, statistical analysis plans, investigator’s brochures, and other key study documents in conjunction with other line functions and with minimal guidance
•
Leads the Project Team, and works with cross-functional team members to define a project strategy and ensure execution against approved strategy
•
Participates in the preparation of regulatory documents in support of regulatory submissions, including clinical section of INDs and CTAs, safety reports, responses to regulatory authorities, clinical study reports, and other documents as appropriate
•
Interfaces with regulatory authorities as appropriate
•
Monitors and/or oversees medical monitoring of clinical studies
•
Participates in business development and strategic planning activities
•
Acts as liaison between clinical development and other internal groups at Vertex for assigned studies
•
Provides medical and development leadership for cross-functional teams
•
Serves on cross-functional study teams for assigned trials, working with other team members to achieve efficient, high-quality study execution, and data analysis
•
Represents Vertex to outside medical personal in the development of clinical protocols and study conduct
Knowledge and Skills:
•
Global clinical research experience, and experience interacting with regulatory authorities is highly desired
•
Ability to work collaboratively in a fast-paced, team-based matrix environment
•
Ability to work independently to resolve challenges
•
Enterprise-wide thinking and ability to work in ambiguity
•
Ability to ensure the completeness of team work
•
Excellent oral and written communication skills
•
Board certification/eligibility in a specialty is highly desired
Education and Experience:
•
MD, DO or equivalent ex-US medical degree
•
Board certification/eligibility in a specialty is highly desired
•
Typically requires 12 years Pharmaceutical/Biotech industry experience, including time managing clinical trials and clinical development programs, or the equivalent combination of education and experience
About the company
At Vertex, we embrace continuous learning and encourage employees to stay informed on advances in AI, technology, automation, and industry trends. We seek talent who bring an external perspective, demonstrate curiosity and sound judgment, and thoughtfully adopt new capabilities that improve decision-making, drive innovation, increase efficiency, and help deliver better outcomes for patients.
Pay Range:
$280,600 - $420,800
Disclosure Statement:
The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law.
Benefits
At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more.
Flex Designation:
Hybrid-Eligible Or On-Site Eligible
Flex Eligibility Status:
In this Hybrid-Eligible role, you can choose to be designated as:
1.
Hybrid: work remotely up to two days per week; or select
2.
On-Site: work five days per week on-site with ad hoc flexibility.
Note: The Flex status for this position is subject to Vertex’s Policy on Flex @ Vertex Program and may be changed at any time.
Company Information
Vertex is a global biotechnology company that invests in scientific innovation.
Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person’s race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.
Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at [email protected]
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