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Vertex

Manager, Disease Strategy Finance

Salary$116k – $174k
LocationBoston, MA
Work modehybrid
Typefull-time
SeniorityMid
Experience5+ yrs
DepartmentFinance
EquityIncluded
Company size10,000+ people
First seenOct 7, 2026 · 4d ago
Verified live1d ago
At a glanceSummarised by Seekless from the posting.
Must have9
B.S. Degree in Finance, Economics, or related quantitative/analytical field
5+ years of relevant finance and industry experience
Understanding of biopharmaceutical drug research, development, manufacturing, and commercialization required
Exceptional analytical and financial skills to evaluate a broad range of financial questions – especially valuation, ROI/ROIC, and complex multi-disciplinary business decisions
Experience with Excel and PowerPoint
Proficient business acumen, judgment and knowledge of the company’s markets/products and industry trends
Strong communication skills, both written and verbal, and an eagerness to collaborate with colleagues
Must be able to work well with senior leaders, peers, and junior team members
Possesses a high degree of attention to detail and ownership over work product with the flexibility to adapt to change
Nice to have4
MBA preferred
Biotechnology/Pharmaceutical industry experience strongly preferred
Experience with biopharma alliance/collaboration accounting preferred though not required
Experience with Hyperion (or another multidimensional database), business intelligence or visualization tools a plus
Skills
Excel
PowerPoint
Hyperion
business intelligence
visualization tools
Benefits
Annual bonus
Equity awards
Medical insurance
Dental insurance
Vision insurance
Paid time off
Educational assistance
Student loan repayment
Commuting subsidy
Charitable donation matching
401(k)
Job Description
The Manager, Disease Strategy Finance is a key member of Vertex’s Disease Strategy Finance Team, providing financial and strategic insights to inform Disease Strategy Teams (“DSTs”) on key decisions. This role will work closely with Directors on the DST Finance team to conduct financial modeling, forecasting, and scenario-based valuations. The Manager, Disease Strategy Finance will also play a critical role in creation of the Annual Budget, Long-Term Plan (LRP), and other financial forecasts in collaboration with colleagues. The role will partner closely with members of the global COFO organization, including finance teams supporting R&D, Biopharmaceutical Sciences and Manufacturing, Corporate, and Commercial. This role offers an opportunity to make a lasting impact by driving profitable growth while creating transformative medicines for people with serious diseases.
Position Summary:
Reporting to the Senior Director, Finance – Disease Strategy Teams, the Manager is a key member of Vertex’s Strategy Finance team and the global FP&A organization. This role will lead financial analysis required to inform Disease Strategy Teams (“DSTs”) on key decisions. Financial analyses will include financial modeling, forecasting, and scenario-based valuations. The Manager FP&A, Strategy Finance will also play a critical role in creating the Annual Budget, Long-Term Plan (LRP), and other financial forecasts. The role will be primary lead for preparation of collaboration financials for both internal and external partner reporting. The role will partner closely with members of the global CFO organization, including finance teams supporting R&D, Biopharmaceutical Sciences and Manufacturing, and Commercial. This role offers an opportunity to make a lasting impact by driving profitable growth while creating transformative medicines for people with serious diseases.
Key Responsibilities:
•
Prepare a wide range of financial analyses to inform DST decisions on investments.
•
Lead preparation of alliance/collaboration financials for revenue/cost sharing in accordance with co-development/co-commercialization contract terms.
•
Develop and maintain financial models covering all aspects of biopharmaceutical research, development, manufacturing, and commercialization.
•
Provide Strategy Finance input into regular financial planning processes (Annual Budget, Forecasts, Long-Range Plan), for assigned Disease Areas.
•
Manage Disease Area P&Ls for assigned DSTs, including ensuring consistent presentation of DST finances across Vertex, explanation of variances vs. forecasts, identification of risks/uncertainties, and opportunities for mitigation.
•
Prepare a wide range of presentations for cross-functional stakeholders and senior leaders.
•
Collaborate throughout CFO organization to identify and deliver on process improvement opportunities.
Qualifications:
•
B.S. Degree in Finance, Economics, or related quantitative/analytical field; MBA preferred.
•
5+ years of relevant finance and industry experience - Biotechnology/Pharmaceutical industry experience strongly preferred.
•
Experience with biopharma alliance/collaboration accounting preferred though not required.
•
Understanding of biopharmaceutical drug research, development, manufacturing, and commercialization required.
•
Exceptional analytical and financial skills to evaluate a broad range of financial questions – especially valuation, ROI/ROIC, and complex multi-disciplinary business decisions.
•
Experience with Excel and PowerPoint; Experience with Hyperion (or another multidimensional database), business intelligence or visualization tools a plus.
•
Proficient business acumen, judgment and knowledge of the company’s markets/products and industry trends.
•
Strong communication skills, both written and verbal, and an eagerness to collaborate with colleagues (within or outside of finance) in sharing insights and learnings. Must be able to work well with senior leaders, peers, and junior team members.
•
Possesses a high degree of attention to detail and ownership over work product with the flexibility to adapt to change.
#HYBRID
About the company
At Vertex, we embrace continuous learning and encourage employees to stay informed on advances in AI, technology, automation, and industry trends. We seek talent who bring an external perspective, demonstrate curiosity and sound judgment, and thoughtfully adopt new capabilities that improve decision-making, drive innovation, increase efficiency, and help deliver better outcomes for patients.
Pay Range:
$116,000 - $174,000
Disclosure Statement:
The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law.
Benefits
At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more.
Flex Designation:
Hybrid-Eligible Or On-Site Eligible
Flex Eligibility Status:
In this Hybrid-Eligible role, you can choose to be designated as:
1.
Hybrid: work remotely up to two days per week; or select
2.
On-Site: work five days per week on-site with ad hoc flexibility.
Note: The Flex status for this position is subject to Vertex’s Policy on Flex @ Vertex Program and may be changed at any time.
Company Information
Vertex is a global biotechnology company that invests in scientific innovation.
Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person’s race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.
Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at [email protected]
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