Postdoctoral Fellow Position - Cancer Epigenetics and Functional Genomics
Read straight from City of Hope's careers page, verified 3d ago.Seekless can tailor your résumé to it.
Seekless can write your résumé for this posting first.
Before you apply
SalaryNo pay range posted
LocationUnited States-California-Duarte
Work modeon-site
Typefull-time
SeniorityEntry
DepartmentCancer Genetics and Epigenetics
Company size10,000+ people
First seenOct 18, 2026 · 2w ago
Verified live3d ago
At a glanceSummarised by Seekless from the posting.
Ph.D. in Cancer Biology, Epigenetics, Molecular Biology, Biochemistry, Genetics, Genomics, or a closely related field
Strong background in chromatin biology, transcriptional regulation, epigenetics, or RNA biology
Extensive hands-on experience in molecular biology and biochemistry techniques
Experience designing, executing, and troubleshooting complex biological experiments independently
Evidence of research productivity demonstrated by first-author publications in peer-reviewed journals
Excellent written and verbal communication skills
Highly self-motivated, creative, and capable of working both independently and collaboratively in a multidisciplinary research environment
Experience with next-generation sequencing-based genomic technologies, including ChIP-seq, CUT&RUN, ATAC-seq, PRO-seq, RNA-seq, or related approaches
Experience performing and interpreting functional genomic experiments related to gene regulation, chromatin organization, or transcription
Familiarity with bioinformatic analysis of genomic or transcriptomic datasets, including command-line tools or commonly used sequencing analysis pipelines
Experience integrating multi-omics datasets to investigate regulatory mechanisms in cancer
Skills
ChIP-seq
CUT&RUN
ATAC-seq
PRO-seq
RNA-seq
CRISPR
single-cell sequencing
next-generation sequencing
bioinformatics
command-line tools
sequencing analysis pipelines
About the company
Join the forefront of groundbreaking research at City of Hope where we’re changing lives and making a real difference in the fight against cancer, diabetes, and other life-threatening illnesses. Our dedicated and compassionate faculty and staff are driven by a common mission: Contribute to innovative approaches in predicting, preventing, and curing diseases, shaping the future of medicine through cutting-edge research.
About the role
The laboratory of Dr. Yanzhong Yangin the Department of Cancer Genetics and Epigenetics at the Beckman Research Institute of City of Hope is seeking a highly motivated Postdoctoral Fellow to investigate mechanisms of chromatin regulation, transcriptional control, and epigenetic signaling in cancer. Research in the Yang laboratory focuses on understanding how protein arginine methylation and methylarginine reader proteins regulate chromatin function, gene expression, RNA processing, and genome organization in normal and disease states. We employ a multidisciplinary approach integrating biochemistry, molecular biology, functional genomics, genome engineering, and computational analyses to uncover fundamental mechanisms of gene regulation and identify novel therapeutic opportunities in human diseases, such as cancer, immune dysregulation, and neuronal disorders.
As a successful candidate you will:
•
Lead independent projects utilizing state-of-the-art genomic and transcriptomic technologies, including ChIP-seq, CUT&RUN, ATAC-seq, PRO-seq, RNA-seq, CRISPR-based functional screens, and single-cell approaches to study epigenetic and transcriptional regulation in cancer.
Your qualifications should include:
•
Ph.D. in Cancer Biology, Epigenetics, Molecular Biology, Biochemistry, Genetics, Genomics, or a closely related field.
•
Strong background in chromatin biology, transcriptional regulation, epigenetics, or RNA biology.
•
Extensive hands-on experience in molecular biology and biochemistry techniques.
•
Experience designing, executing, and troubleshooting complex biological experiments independently.
•
Evidence of research productivity demonstrated by first-author publications in peer-reviewed journals.
•
Excellent written and verbal communication skills.
•
Highly self-motivated, creative, and capable of working both independently and collaboratively in a multidisciplinary research environment.
Preferred qualifications:
•
Experience with next-generation sequencing-based genomic technologies, including ChIP-seq, CUT&RUN, ATAC-seq, PRO-seq, RNA-seq, or related approaches.
•
Experience performing and interpreting functional genomic experiments related to gene regulation, chromatin organization, or transcription.
•
Familiarity with bioinformatic analysis of genomic or transcriptomic datasets, including command-line tools or commonly used sequencing analysis pipelines.
•
Experience integrating multi-omics datasets to investigate regulatory mechanisms in cancer.
City of Hope employees pay is based on the following criteria: work experience, qualifications, and work location.
City of Hope is an equal opportunity employer.
Benefits
To learn more about our Comprehensive Benefits, pleaseCLICK HERE.
Please note: City of Hope is committed to a safe and transparent hiring experience. Please be aware that scammers may attempt to impersonate our organization through fake job postings, emails or interviews.
•
Apply only through our official website or trusted partner platforms.
•
City of Hope will never request payment or fees at any stage of the hiring process.
•
We will not request sensitive personal or financial information prior to the acceptance of a formal offer.
•
All communications will come from official @coh.org email addresses.
•
Interviews are conducted only through approved, professional channels.
•
Be cautious of unsolicited communications, urgent requests or opportunities that seem inconsistent with standard hiring practices.
•