Shriners Children’s Research Institute (SCRI) is a newly established research organization designed to advance translational science and accelerate innovation in pediatric medicine. Located in Atlanta, Georgia’s Science Square innovation district, SCRI will occupy a 150,000-square-foot, state-of-the-art facility focused on tissue engineering, genomics, movement science, artificial intelligence, clinical informatics, augmented reality, and biomanufacturing. By leveraging Shriners Children’s global network of pediatric specialists, hospitals, and outreach clinics, SCRI aims to transform groundbreaking research into clinical solutions that improve children’s health worldwide.