Principal Associate Scientist
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Before you apply
Salary$112k – $118k
LocationBoston, MA
Typefull-time
SeniorityLead
Experience3+ yrs
DepartmentR&D
Company size1+ people
PostedOct 27, 2026 · 1w ago
Verified live5d ago
At a glanceSummarised by Seekless from the posting.
Master's Degree in Molecular/Cellular Biology, Biochemistry, or related field and 3 years related experience, or Bachelor's Degree and 5 years related experience
Experience in RNA therapeutics with a focus on pre-mRNA splicing and protein translation
Designing and cloning RNA exon-editing molecules
Designing assays to measure RNA editing
Optimization and preparation of custom Illumina libraries
Bioinformatic analysis of the libraries
Cell culture, ddPCR, qPCR and protein extraction and characterization by JESS and western blot, Sanger sequence analysis
Use of sequence design and analysis software
Skills
ddPCR
qPCR
JESS
western blot
sequence design and analysis software
cell culture
bioinformatics
Illumina
Sanger sequence analysis
About the role
(Boston, MA) Principal Associate Scientist sought by Ascidian Therapeutics, Inc. to
design, validate, execute, and interpret experiments to improve therapeutic performance
of designer RNA editing molecules & contribute to characterization of drug candidates to
support Ascidian’s Roche Collaboration. Req.’s Master’s Deg. in Molecular/Cellular
Bio., Bio. Chem. or rel. field & 3 yrs rel. exp. or Bach’s Deg. & 5 yrs rel. exp. Must have
experience in RNA therapeutics with a focus on pre-mRNA splicing and protein
translation; designing and cloning RNA exon-editing molecules and designing assays to
measure RNA editing; optimization and preparation of custom Illumina libraries;
bioinformatic analysis of the libraries; cell culture, ddPCR, qPCR and protein extraction
and characterization by JESS and western blot, Sanger sequence analysis; use of
sequence design and analysis software.
No calls.
Salary: $ 112,017 to $118,400 per year.
Legal
The final salary offer will be determined based on several factors, including the candidate’s relevant experience, specific skills, and internal equity.