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Vertex

Principal Programmer, Statistical Programming (Remote)

Salary$149k – $224k
LocationBoston, MA
Work moderemote · United States
Typefull-time
SeniorityLead
Experience5+ yrs
EquityIncluded
Company size10,000+ people
First seenOct 7, 2026 · 4d ago
Verified live1d ago
At a glanceSummarised by Seekless from the posting.
Must have7
Proficiency in all SAS language, procedures, and functions commonly used in clinical trial reporting including the Macro language, BASE SAS, SAS/STAT and SAS/GRAPH
Intermediate knowledge of CDISC Standards
Intermediate knowledge of clinical trials
Regulatory submission experiences
Effective communication (written and verbal) skills to explain difficult information
Bachelors degree in a Scientific Discipline
5+ for M.S. or above and 8+ years for B.S. years of work experience in Biotech, Pharmaceuticals or Clinical Research Organization
Skills
SAS
CDISC
Benefits
Health insurance
Dental insurance
Vision insurance
Paid time off
Educational assistance
401(k)
Commuting subsidy
Charitable donation matching
Annual bonus
Equity awards
Job Description
General Summary:
The Principal Statistical Programmer works with management to delegate tasks appropriately, track progress, and provide expert technical support to team members. In addition, the Principal Statistical Programmer is a designated member of clinical sub-team(s) in the role of project lead Statistical Programmer.
Key Duties and Responsibilities:
•
Works regularly with advanced features of SAS (including interfacing ability with other software applications and operating system tools)
•
Performs quality control checks of SAS code and output produced by other Statistical Programmers to ensure accuracy and consistency within group
•
Demonstrates in-depth knowledge of clinical development and medical data
•
Solves complex clinical trial reporting problems and demonstrates technical proficiency and exercises judgment in supporting daily operations and ensuring that study tasks are completed accurately and in a timely manner
•
Engages with a variety of other functions, including Statistical Programmers, Biostatisticians, Data Management, and other departments engaged in providing data and submission-related activities, often at Senior Management levels
•
Creates all files, documents, and analyses necessary to support an electronic submission in eCTD format, including ISS/ISE
•
Provides leadership to ensure compliance with Vertex SOP’S and FDA/ICH/GCP regulations
•
Provides technical and project management skills to create, review, and approve documentation required to support data analysis, reporting, and CDlSC data submission
•
Participates in project management cross-functional teams that work on standard operating procedures, guidelines, process improvements, system validation and acquisition, customization, and integration of new tools and technologies
Knowledge and Skills:
•
Proficiency in all SAS language, procedures, and functions commonly used in clinical trial reporting including the Macro language, BASE SAS, SAS/STAT and SAS/GRAPH
•
Intermediate knowledge of CDISC Standards
•
Intermediate knowledge of clinical trials
•
Regulatory submission experiences
•
Effective communication (written and verbal) skills to explain difficult information
Education and Experience:
•
Bachelors degree in a Scientific Discipline
•
Typically requires 5+ for M.S. or above and 8+ years for B.S. years of work experience in Biotech, Pharmaceuticals or Clinical Research Organization
Pay Range 136,960.00 – 205,440.00 USD annually
Legal
The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law.
Benefits
At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more.
About the company
At Vertex, we embrace continuous learning and encourage employees to stay informed on advances in AI, technology, automation, and industry trends. We seek talent who bring an external perspective, demonstrate curiosity and sound judgment, and thoughtfully adopt new capabilities that improve decision-making, drive innovation, increase efficiency, and help deliver better outcomes for patients.
Pay Range:
$149,200 - $223,800
Disclosure Statement:
The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law.
At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more.
Flex Designation:
Remote-Eligible
Flex Eligibility Status:
In this Remote-Eligible role, you can choose to be designated as:
1.
Remote: work remotely five days per week and come into the office on occasion – you’re always welcome on-site; or select
2.
Hybrid: work remotely up to two days per week; or select
3.
On-Site: work five days per week on-site with ad hoc flexibility.
Note: The Flex status for this position is subject to Vertex’s Policy on Flex @ Vertex Program and may be changed at any time.
Company Information
Vertex is a global biotechnology company that invests in scientific innovation.
Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person’s race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.
Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at [email protected]
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