POSITION DESCRIPTION: Takeda Development Center Americas, Inc. is seeking a Digital Drug Product Development Senior Research Associate with the following duties: develop robust drug product formulations across the product lifecycle, including development and tech transfer of scalable, robust drug product manufacturing processes from early phase through process validation; apply computational fluid dynamics (CFD) with a strong focus on mixing and filtration operations to understand, design, and optimize drug product unit operations; utilize CFD principles and tools (including M-Star CFD) to build and deploy digital twins of drug product development processes, enabling mechanistic understanding of mixing, suspension uniformity, shear exposure, filtration performance, and scale-up risk; provide technical leadership and guidance for formulation and drug product development, author technical protocols, design and execute experiments, generate technical reports, and contribute to CMC sections supporting regulatory submissions; lead and support in silico, simulation, and digital twin initiatives, integrating CFD-based mixing and filtration models with experimental data; apply modern computational approaches including machine learning, data analytics, statistical and chemometric methods—to traditional pharmaceutical formulation and process development challenges; deliver applied data science, predictive modeling, and mechanistic process modeling support across multiple projects to enable robust process development, scale-up, and validation. Up to 10% domestic travel required for conference presentations, and site visits of CDMO and manufacturers. Up to 20% remote work allowed.