Cellular Biologist
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Before you apply
SalaryNo pay range posted
LocationSouth San Francisco
Work modeon-site
Typefull-time
SeniorityMid
DepartmentLab
Company size3+ people
PostedSep 30, 2026 · 1mo ago
Verified live2d ago
At a glanceSummarised by Seekless from the posting.
Strong foundation in mammalian cell culture and cellular assay development
Experience with disease-relevant cellular models
Ability to troubleshoot complex biological systems and optimize experimental protocols
Track record of productivity and effective collaboration
PhD in cell and molecular biology with focus on disease models
Industry experience in drug discovery or biotech
Experience with reporter assays and high-throughput screening platforms
Familiarity with oncology, neurodegeneration, or metabolic disease models
Track record of developing novel cellular assays or screening approaches
Topos Bio
At Topos Bio, we’re pioneering drug discovery for intrinsically disordered proteins—targets that have eluded conventional approaches in neurodegeneration, oncology, and cardiometabolic disease.
About the role
We’re seeking a cell biologist to develop and execute cell-based assays for validating computational predictions and supporting medicinal chemistry efforts. You’ll work at the interface of disease biology, protein biophysics, and drug screening.
What you will do
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Develop and optimize mammalian cell-based assays for disordered protein targets
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Execute phenotypic and reporter-based screening campaigns to validate computational hits
•
Characterize compound activity and support structure-activity relationship studies
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Collaborate with computational scientists to integrate experimental data with modeling workflows
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Establish robust assay protocols and quality control metrics
What we are looking for
•
Strong foundation in mammalian cell culture and cellular assay development
•
Experience with disease-relevant cellular models
•
Ability to troubleshoot complex biological systems and optimize experimental protocols
•
Track record of productivity and effective collaboration
Preferred
•
PhD in cell and molecular biology with focus on disease models
•
Industry experience in drug discovery or biotech
•
Experience with reporter assays and high-throughput screening platforms
•
Familiarity with oncology, neurodegeneration, or metabolic disease models
•
Track record of developing novel cellular assays or screening approaches
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