Research Associate II – Islet Biology and Diabetes Mouse Models
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Before you apply
SalaryNo pay range posted
LocationUnited States-California-Duarte
Work modeon-site
Typefull-time
SeniorityMid
Experience1+ yrs
Company size10,000+ people
First seenOct 18, 2026 · 2w ago
Verified live1d ago
At a glanceSummarised by Seekless from the posting.
Bachelor's degree in Biological Sciences or related field
2 years of post-degree research experience
Master's degree in Biological Sciences or related field
1 year of post-degree research experience
Prior experience in islet biology
Prior experience with mouse metabolic phenotyping
Prior experience with diabetic mouse models
Skills
fluorescence microscopy
proteomics
RNAseq
CRISPR-Cas9
About the company
Join the forefront of groundbreaking research at theBeckman Research Institute of City of Hope, where we’re changing lives and making a real difference in the fight against cancer, diabetes, and other life-threatening illnesses. Our dedicated and compassionate faculty and staff are driven by a common mission: Contribute to innovative approaches in predicting, preventing, and curing diseases, shaping the future of medicine through cutting-edge research.
About the role
A Research Associate II is available within the lab of Dr. Sharon Alterzon.The Baumel-Alterzon research lab focuses on studying the importance of redox regulation in the survival, expansion and differentiation of pancreatic beta-cells, aiming to identify therapeutic targets for beta-cell resilience and regeneration in diabetes. Research involves the use of diabetic mouse models, isolated primary islets, and stem cell-derived islets, employing techniques such as fluorescence microscopy, proteomics, RNAseq, CRISPR-Cas9, and genetically-modified mouse model characterization. Prior experience in islet biology and with mouse metabolic phenotyping and diabetic mouse models is a plus
Responsibilities
Under general supervision of the Principal Investigator, or designee, you will perform assays to support research studies, assist in the interpretation of research outcomes, analyze data using computer-based approaches, train new staff on various techniques, and assist in the clerical and supply aspects of the laboratory environment.
As a successful candidate, you will:
· Perform a variety of routine and non-routine laboratory research experiments. Record and validate results for accuracy and completeness.
· Troubleshoot procedures if experiment results are unexpected or unsatisfactory. Recommend alternative procedures.
· Accurately record work performed including results and methodology. Calculate, compile, and analyze data obtained from work performed.
· Independently evaluate research data and initiate alternative approaches to improve the quality of results by providing input to overall research design. Train lab staff in specialized procedures, equipment, and theoretical concepts behind unique tests.
· May contribute to the preparation of manuscripts by describing methods and specialized techniques. Keep abreast of new and improved techniques.
· Ensure that all laboratory activities are carried out in compliance with each procedure(s) by utilizing safety procedures and guidelines in handling, storage and disposal of bio-hazardous, infectious and toxic material.
Your qualifications should include:
· Bachelor’s degree in Biological Sciences or related field, with 2 years of post-degree research experience, or 1 year with a Master’s degree
City of Hope employees pay is based on the following criteria: work experience, qualifications, and work location.
City of Hope is an equal opportunity employer.
Benefits
To learn more about our Comprehensive Benefits, please CLICK HERE.